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October 2021

Fully artificial pancreas vs hybrid artificial pancreas for type-1 diabetes

Seems like a viable option. Larger, long-terme studies are needed.

From the abstract:

Findings Between Feb 8, 2019, and Sept 19, 2020, we enrolled 28 adults, of whom 24 completed both interventions and were included in analyses. The percentage of time spent in the target range was 74·3% (IQR 61·5–82·8) with the fully closed-loop system versus 78·1% (66·3–87·5) with the hybrid Fiasp-alone closed-loop system (paired difference 2·6%, 95% CI –2·4 to 12·2; non-inferiority p=0·28). Eight (33%) participants had at least one hypoglycaemia event (<3·3 mmol/L) with the fully closed-loop system compared with 14 (58%) participants with the hybrid closed-loop system (2200–2200 h).

Full study can be found in The Lancet